Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698150 | 0.85 | LMNA (0.48) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL5814537 | 0.84 | LMNA (0.59) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL27397925 | 0.84 | LMNA (0.59) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL18687134 | 0.78 | LMNA (0.43) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL22227972 | 0.77 | LMNA (0.61) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL27398015 | 0.76 | NPC1 (0.49) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL17150252 | 0.73 | LMNA (0.51) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL27397970 | 0.72 | LMNA (0.53) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL18083396 | 0.72 | LMNA (0.45) | LMNACYP1A2CYP2D6CYP2C19BCHE | |
| SCHEMBL8573940 | 0.71 | LMNA (0.51) | LMNACYP1A2CYP2D6CYP2C19BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150604-B1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO (JP) | 2021-07-14 | — | — | EP | disclosed |
| EP-3150604-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-05 | — | — | EP | disclosed |