Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 3/20 | 0.34 |
| ▸ | BCOR | Q6W2J9 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698530 | 0.81 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL17304107 | 0.80 | HTR6 (0.43) | BCL6BCORALKHTR2AHTR2C | |
| SCHEMBL30640822 | 0.80 | HTR6 (0.43) | BCL6BCORALKHTR2AHTR2C | |
| SCHEMBL30640827 | 0.80 | GRIA1 (0.36) | BCL6BCORALKUTS2RHTR2A | |
| SCHEMBL17303749 | 0.80 | GRIA1 (0.36) | BCL6BCORALKUTS2RHTR2A | |
| SCHEMBL18698393 | 0.75 | HTR6 (0.34) | BCL6BCORALKHTR2A | |
| SCHEMBL17304121 | 0.74 | BCL6 (0.42) | BCL6BCOR | |
| SCHEMBL17304076 | 0.71 | PDE3B (0.35) | BCL6BCOR | |
| SCHEMBL17304089 | 0.71 | SLC6A4 (0.32) | BCL6BCORSLC6A4 | |
| SCHEMBL17304105 | 0.71 | SLC6A4 (0.45) | SLC6A4ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150592-A1 | ALK KINASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | Beijing Pearl Biotechnology Limited Liability Company (CN) | 2017-04-05 | — | — | EP | disclosed |