SCHEMBL1869871

SCHEMBL1869871

C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@@]2(O)CO

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
G6PD P11413 3/20 0.67
SERPINA6 P08185 2/20 0.64
LMNA P02545 2/20 0.60
GPBAR1 Q8TDU6 2/20 0.60
CYP1A2 P05177 2/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2C9 P11712 2/20 0.60
TSHR P16473 2/20 0.60
SHBG P04278 1/20 0.60
CYP2C19 P33261 1/20 0.60
HSD17B10 Q99714 1/20 0.60
ALDH1A1 P00352 1/20 0.57
MAPT P10636 1/20 0.57
PMP22 Q01453 1/20 0.57
KMT2A Q03164 1/20 0.57
NR1I3 Q14994 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16226265 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL16226587 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL16226634 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL16226069 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL4934329 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL1872625 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL16225749 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL9436439 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL16225853 1.00 G6PD (0.67) G6PDSERPINA6LMNAGPBAR1CYP1A2
SCHEMBL598190 0.90 G6PD (0.64) G6PDSERPINA6LMNAGPBAR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080038316-A1 Conveniently implantable sustained release drug compositions RAMSCOR, INC. 2008-02-14 US claimed
JP-3378245-B2 2003-02-17 JP claimed
US-6011023-A Angiostatic steroids ALCON LABORATORIES, INC. (US) 2000-01-04 US claimed
US-5371078-A Angiostatic steroids and methods and compositions for controlling ocular hypertension ALCON LABORATORIES, INC. (US) 1994-12-06 US claimed
EP-0614463-A1 ANGIOSTATIC STEROIDS ALCON LABORATORIES, INC. (US) 1994-09-14 EP claimed
WO-1993010141-A2 ANGIOSTATIC STEROIDS ALCON LABORATORIES, INC. (US) 1993-05-27 WO claimed
US-20200316265-A1 MULTIPHASE GEL BVW HOLDING AG (CH) 2020-10-08 US disclosed
US-10744202-B2 Sustained release eye drop formulations RAMSCOR, INC. (US) 2020-08-18 US disclosed
US-10668190-B2 Multiphase gel BVW HOLDING AG (CH) 2020-06-02 US disclosed
US-20180289810-A1 SUSTAINED RELEASE EYE DROP FORMULATIONS RAMSCOR, INC. (US) 2018-10-11 US disclosed
US-9981041-B2 Ophthalmic lubricating spray SALZMAN IRA JASON (US) 2018-05-29 US disclosed
US-20180055943-A1 OPHTHALMIC LUBRICATING SPRAY SALZMAN IRA JASON (US) 2018-03-01 US disclosed
US-20170319751-A1 Multiphase Gel BVW HOLDING AG (CH) 2017-11-09 US disclosed
US-20110111006-A1 CONVENIENTLY IMPLANTABLE SUSTAINED RELEASE DRUG COMPOSITIONS RAMSCOR, INC. (US) 2011-05-12 US disclosed
US-7906136-B2 Conveniently implantable sustained release drug compositions RAMSCOR, INC. (US) 2011-03-15 US disclosed
US-20090136445-A1 SUSTAINED RELEASE EYE DROP FORMULATIONS RAMSCOR, INC. 2009-05-28 US disclosed
US-20080038316-A1 Conveniently implantable sustained release drug compositions RAMSCOR, INC. 2008-02-14 US disclosed
EP-1236469-A2 Angiostatic steroids Alcon Laboratories, Inc. (US) 2002-09-04 EP disclosed
EP-1236471-A2 Angiostatic steroids Alcon Laboratories, Inc. (US) 2002-09-04 EP disclosed
EP-1236470-A2 Angiostatic steroids Alcon Laboratories, Inc. (US) 2002-09-04 EP disclosed