Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of 1-Ethylquinolonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 13/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | RGS12 | O14924 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | RAD52 | P43351 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 12/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Ethylquinolonium SCHEMBL30920082 | 1.00 | KDM4E (0.62) | KDM4EMEN1RGS12NPC1USP2 | |
| 1-Ethylquinolonium SCHEMBL309459 | 0.98 | ACHE (0.63) | KDM4EMEN1RGS12NPC1USP2 | |
| 1-Ethylquinolonium SCHEMBL9135771 | 0.96 | ACHE (0.62) | KDM4EMEN1RGS12NPC1USP2 | |
| 1-Ethylquinolonium SCHEMBL10655763 | 0.96 | ACHE (0.64) | ACHEBCHE | |
| 1-Ethylquinolonium SCHEMBL18804795 | 0.96 | ACHE (0.61) | KDM4EMEN1RGS12NPC1USP2 | |
| 1-Ethylquinolonium SCHEMBL4624855 | 0.90 | ACHE (0.55) | KDM4EMEN1RGS12NPC1USP2 | |
| 1-Ethylquinolonium SCHEMBL28221155 | 0.90 | ACHE (0.55) | KDM4EMEN1RGS12NPC1USP2 | |
| 1-Ethylquinolonium SCHEMBL29623615 | 0.88 | ACHE (0.53) | KDM4EMEN1RGS12NPC1USP2 | |
| 1-Ethylquinolonium SCHEMBL9645182 | 0.85 | ACHE (0.50) | KDM4EMEN1RGS12NPC1USP2 | |
| Iodide SCHEMBL4618173 | 0.83 | KDM4E (0.74) | KDM4EMEN1RGS12NPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403959-B | Preparation method of polarity-difference multicolor resin coating stock solution | 扬州市祥华新材料科技有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-115403959-A | Preparation method of colorful resin coating stock solution with polarity difference | 扬州市祥华新材料科技有限公司 | 2022-11-29 | — | — | CN | claimed |
| US-5607815-A | CONTAINING ARYLHYDRAZIDE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-04 | — | — | US | claimed |
| US-5384232-A | Process for rapid access development of silver halide films using pyridinium as development accelerators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-24 | — | — | US | claimed |
| US-4209418-A | CLEANING SOLUTIONS FOR METAL INDUSTRIAL EQUIPMENT | UNION CARBIDE CORPORATION (US) | 1980-06-24 | — | — | US | claimed |
| US-20250033015-A1 | POLYDISULFIDE CORE-SHELL MICROCAPSULES | FIRMENICH SA (CH) | 2025-01-30 | — | — | US | disclosed |
| EP-4448159-A1 | POLYDISULFIDE CORE-SHELL MICROCAPSULES | Firmenich SA (CH) | 2024-10-23 | — | — | EP | disclosed |
| CN-115403959-B | Preparation method of polarity-difference multicolor resin coating stock solution | 扬州市祥华新材料科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| WO-2023111039-A1 | POLYDISULFIDE CORE-SHELL MICROCAPSULES | FIRMENICH SA (CH) | 2023-06-22 | — | — | WO | disclosed |
| CN-115403959-A | Preparation method of colorful resin coating stock solution with polarity difference | 扬州市祥华新材料科技有限公司 | 2022-11-29 | — | — | CN | disclosed |
| US-20190040209-A1 | METHODS FOR DISSOLVING POLYMERS USING MIXTURES OF DIFFERENT IONIC LIQUIDS AND COMPOSITIONS COMPRISING THE MIXTURES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA | 2019-02-07 | — | — | US | disclosed |
| EP-2257669-B1 | IONIC LIQUID SYSTEMS FOR THE PROCESSING OF BIOMASS, THEIR COMPONENTS AND/OR DERIVATIVES, AND MIXTURES THEREOF | UNIV ALABAMA (US) | 2017-03-22 | — | — | EP | disclosed |
| US-4587056-A | CARBONYLATION, OXIDATION, CATALYST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-05-06 | — | — | US | disclosed |
| EP-0161550-A1 | Process for producing an aliphatic isocyanate | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-11-21 | — | — | EP | disclosed |
| US-4554383-A | Process for producing p-tolualdehyde from toluene using an aluminum halide alkyl pyridinium halide `melt` catalyst | TEXACO INC. (US) | 1985-11-19 | — | — | US | disclosed |
| EP-0037190-B1 | METHOD OF ELECTROLYTICALLY DECONTAMINATING COMPONENTS OF NUCLEAR REACTOR SYSTEM | WESTINGHOUSE ELECTRIC CORPORATION (US) | 1985-07-03 | — | — | EP | disclosed |
| US-4451679-A | RUTHENIUM COMPOUNDS, PHOSPHONIUM OR QUATERNARY AMMONIUM COMPOUNDS | TEXACO INC. (US) | 1984-05-29 | — | — | US | disclosed |
| EP-0107430-A2 | Method for the preparation of alcohols and aldehydes by reacting olefins with carbon monoxide and hydrogen | TEXACO DEVELOPMENT CORPORATION (US) | 1984-05-02 | — | — | EP | disclosed |
| US-4318786-A | Electrolytic decontamination | WESTINGHOUSE ELECTRIC CORP. (US) | 1982-03-09 | — | — | US | disclosed |
| US-4209418-A | CLEANING SOLUTIONS FOR METAL INDUSTRIAL EQUIPMENT | UNION CARBIDE CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |