SCHEMBL18699588

SCHEMBL18699588

C=C(C)C(=O)Oc1ccc(-c2ccc(-c3ccc(OC)cc3)c(F)c2F)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.48
ELANE P08246 1/20 0.47
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 3/20 0.43
ATM Q13315 1/20 0.43
CYP2C19 P33261 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
APP P05067 1/20 0.43
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9607858 0.94 ELANE (0.51) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL18869481 0.92 BACE1 (0.49) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL12196860 0.90 ELANE (0.43) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL9607785 0.88 ELANE (0.47) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL21322428 0.87 ELANE (0.46) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL13639988 0.87 ELANE (0.46) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL18432941 0.86 CYP2C19 (0.51) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL19881850 0.86 ELANE (0.56) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL18104469 0.86 ELANE (0.56) BACE1ELANEMAPTSMN1; SMN2KMT2A
SCHEMBL22600469 0.86 ELANE (0.44) BACE1ELANEMAPTSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306614-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-3628721-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-03-01 EP disclosed
EP-3944011-A1 LIQUID-CRYSTAL DISPLAY Merck Patent GmbH (DE) 2022-01-26 EP disclosed
EP-3257916-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2021-11-17 EP disclosed
EP-3839620-A1 DEVICE FOR THE REGULATION OF LIGHT TRANSMISSION Merck Patent GmbH (DE) 2021-06-23 EP disclosed
EP-3353261-B1 METHOD OF CONTROLLING THE PRETILT ANGLE IN POLYMER STABILISED LIQUID CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2020-05-27 EP disclosed
EP-2918658-B1 Liquid crystalline media with homeotropic alignment MERCK PATENT GMBH (DE) 2020-05-13 EP disclosed
EP-3628721-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2020-04-01 EP disclosed
EP-3174955-B1 LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2019-10-23 EP disclosed
EP-3130651-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-10-16 EP disclosed
EP-2985334-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-20 EP disclosed
EP-3083408-B1 FILLING DEVICE AND USE THEREOF FOR FILLING A FLUID MERCK PATENT GMBH (DE) 2018-02-21 EP disclosed
EP-3260518-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-12-27 EP disclosed
EP-3029127-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-12-20 EP disclosed
EP-3257916-A1 LIQUID CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-12-20 EP disclosed
EP-2909286-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-11-22 EP disclosed
EP-2855628-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-09-06 EP disclosed
EP-2993216-B1 COMPOUNDS AND LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-07-26 EP disclosed
EP-2848676-B1 Liquid crystal medium MERCK PATENT GMBH (DE) 2017-07-26 EP disclosed
EP-2937401-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-04-05 EP disclosed