Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956316 | 0.90 | ADAM17 (1.00) | ADAM17TNF | |
| SCHEMBL10131390 | 0.89 | ADAM17 (0.83) | ADAM17TNF | |
| SCHEMBL10131348 | 0.89 | ADAM17 (0.83) | ADAM17TNF | |
| SCHEMBL7904506 | 0.88 | ADAM17 (1.00) | ADAM17TNF | |
| SCHEMBL7898207 | 0.88 | ADAM17 (0.82) | ADAM17TNF | |
| SCHEMBL8227108 | 0.88 | ADAM17 (1.00) | ADAM17TNF | |
| SCHEMBL8233011 | 0.88 | ADAM17 (0.82) | ADAM17TNF | |
| SCHEMBL5956211 | 0.88 | ADAM17 (1.00) | ADAM17TNF | |
| SCHEMBL12860693 | 0.88 | ADAM17 (0.78) | ADAM17TNF | |
| SCHEMBL12860697 | 0.87 | ADAM17 (0.81) | ADAM17TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973900-B1 | HYDANTOIN COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | MERCK SHARP & DOHME (US) | 2017-04-05 | — | — | EP | disclosed |