Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 19/20 | 0.61 |
| ▸ | NPY1R | P25929 | 11/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.61 |
| ▸ | NPY2R | P49146 | 7/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22374931 | 0.89 | QRFPR (0.52) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL22374927 | 0.89 | QRFPR (0.52) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL11209257 | 0.88 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29442111 | 0.88 | NPY4R (0.69) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29442083 | 0.86 | NPY4R (0.65) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL22374954 | 0.86 | TFPI (0.55) | — | |
| SCHEMBL29442105 | 0.85 | TFPI (0.61) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL8741197 | 0.84 | NPY4R (0.60) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL9141613 | 0.84 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL22375051 | 0.83 | QRFPR (0.51) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611293-B2 | Synthesis of beta-arrestin effectors | TREVENA, INC. (US) | 2017-04-04 | — | — | US | disclosed |