Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704173 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAKMT2APOLBNPC1 | |
| SCHEMBL18704169 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNAKMT2APOLBNPC1 | |
| SCHEMBL18704218 | 0.78 | FFAR1 (0.36) | LMNAKMT2APOLBL3MBTL1MEN1 | |
| SCHEMBL18704217 | 0.78 | FFAR1 (0.36) | LMNAKMT2APOLBL3MBTL1MEN1 | |
| SCHEMBL18704147 | 0.78 | FFAR1 (0.47) | LMNAKMT2AMEN1 | |
| SCHEMBL18704145 | 0.78 | FFAR1 (0.47) | LMNAKMT2AMEN1 | |
| SCHEMBL20661145 | 0.70 | UTS2R (0.38) | SMN1; SMN2KMT2ARAB9AL3MBTL1MEN1 | |
| SCHEMBL20660957 | 0.69 | AOC3 (0.40) | SMN1; SMN2LMNAKMT2ARAB9AMAPT | |
| SCHEMBL4024996 | 0.68 | LMNA (0.32) | LMNAKMT2A | |
| SCHEMBL16263403 | 0.68 | KCNA5 (0.42) | KMT2AL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060488-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2017-04-13 | — | — | WO | disclosed |