Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704165 | 0.72 | KDM4C (0.40) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL9923393 | 0.71 | KDM4C (0.37) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL19715580 | 0.70 | KDM4C (0.41) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL25228564 | 0.69 | KDM4C (0.43) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL3889222 | 0.69 | KDM4C (0.46) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL30486438 | 0.69 | KDM4C (0.43) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL24006607 | 0.69 | KDM4C (0.41) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL21157983 | 0.69 | KDM4C (0.41) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL22275457 | 0.69 | KDM4C (0.41) | KDM4CL3MBTL1RAB9ANPC1MEN1 | |
| SCHEMBL2884836 | 0.68 | ICAM1 (0.42) | KDM4CL3MBTL1RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060488-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2017-04-13 | — | — | WO | disclosed |