Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19715580 | 0.70 | KDM4C (0.41) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL30486563 | 0.70 | KDM4C (0.47) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL21156721 | 0.70 | KDM4C (0.37) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL25229073 | 0.70 | KDM4C (0.47) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL1564762 | 0.70 | PDE4A (0.38) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL29447793 | 0.70 | KDM4C (0.40) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL2006340 | 0.70 | TACR1 (0.45) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL25247290 | 0.69 | MEN1 (0.36) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL12168828 | 0.69 | ICAM1 (0.43) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL7737544 | 0.69 | KDM4C (0.43) | KDM4CL3MBTL1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019126085-A1 | PYRAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-06-27 | — | — | WO | disclosed |