Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704240 | 0.88 | ALDH1A1 (0.47) | ALDH1A1TSHRHCAR2LMNAESR1 | |
| SCHEMBL7565591 | 0.83 | MEN1 (0.52) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL28063852 | 0.79 | MEN1 (0.37) | MEN1KMT2AALDH1A1TSHRHCAR2 | |
| SCHEMBL28631996 | 0.76 | MEN1 (0.38) | MEN1KMT2AALDH1A1TSHRHCAR2 | |
| SCHEMBL130111 | 0.76 | HCAR2 (0.39) | ALDH1A1TSHRHCAR2LMNAESR1 | |
| SCHEMBL685430 | 0.76 | HCAR2 (0.39) | ALDH1A1TSHRHCAR2LMNAESR1 | |
| SCHEMBL6062638 | 0.75 | HCAR2 (0.41) | ALDH1A1TSHRHCAR2LMNAESR1 | |
| SCHEMBL204763 | 0.75 | POLB (0.44) | ALDH1A1TSHRHCAR2LMNAESR1 | |
| SCHEMBL19033723 | 0.75 | MEN1 (0.37) | MEN1KMT2AALDH1A1TSHRHCAR2 | |
| SCHEMBL28817931 | 0.75 | MEN1 (0.33) | MEN1KMT2AALDH1A1TSHRHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202352-B2 | Process for preparation of aminopyrazole | GHARDA CHEMICALS LIMITED (IN) | 2019-02-12 | — | — | US | claimed |
| US-20180282284-A1 | PROCESS FOR PREPARATION OF AMINOPYRAZOLE | GHARDA CHEMICALS LIMITED (IN) | 2018-10-04 | — | — | US | claimed |
| WO-2017060787-A1 | PROCESS FOR PREPARATION OF AMINOPYRAZOLE | GHARDA CHEMICALS LIMITED (IN) | 2017-04-13 | — | — | WO | claimed |
| US-10202352-B2 | Process for preparation of aminopyrazole | GHARDA CHEMICALS LIMITED (IN) | 2019-02-12 | — | — | US | disclosed |
| US-20180282284-A1 | PROCESS FOR PREPARATION OF AMINOPYRAZOLE | GHARDA CHEMICALS LIMITED (IN) | 2018-10-04 | — | — | US | disclosed |
| WO-2017060787-A1 | PROCESS FOR PREPARATION OF AMINOPYRAZOLE | GHARDA CHEMICALS LIMITED (IN) | 2017-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202352-B2 | Process for preparation of aminopyrazole | CYP3A4, CYP3A5, CYP4F3 | MEN1 3649/4885KMT2A 2262/4885ALDH1A1 1320/4885 |
| US-20180282284-A1 | PROCESS FOR PREPARATION OF AMINOPYRAZOLE | CYP3A4, CYP3A5, CYP4F3 | MEN1 3649/4885KMT2A 2262/4885ALDH1A1 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.