Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 13/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724020 | 0.89 | BCL2 (0.45) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL2724230 | 0.86 | BCL2 (0.47) | BCL2BCL2L1 | |
| SCHEMBL2725535 | 0.86 | BCL2 (0.49) | BCL2BCL2L1 | |
| SCHEMBL2723940 | 0.86 | BCL2 (0.49) | BCL2BCL2L1 | |
| SCHEMBL1870158 | 0.85 | BCL2 (0.45) | BCL2BCL2L1 | |
| SCHEMBL2724331 | 0.84 | BCL2 (0.55) | BCL2BCL2L1 | |
| SCHEMBL2727803 | 0.83 | BCL2 (0.47) | BCL2BCL2L1CYP2C9 | |
| SCHEMBL2725898 | 0.83 | BCL2 (0.49) | BCL2BCL2L1 | |
| SCHEMBL30622009 | 0.83 | BCL2 (0.54) | BCL2BCL2L1 | |
| SCHEMBL30622019 | 0.83 | BCL2 (0.50) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138588-A9 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | claimed |