SCHEMBL18705346

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18736244	0.97	TDP1 (0.56)	TDP1PKMMEN1ABL1LMNA
	SCHEMBL18736525	0.95	ADORA2A (0.53)	TDP1PKMMEN1ABL1LMNA
	SCHEMBL23125939	0.92	TDP1 (0.51)	TDP1PKMMEN1ABL1LMNA
	SCHEMBL18736240	0.91	FOLH1 (0.58)	TDP1PKMMEN1ABL1LMNA
	SCHEMBL20519904	0.91	FOLH1 (0.59)	TDP1PKMCSNK2A2CSNK2BCSNK2A1
	SCHEMBL18705344	0.90	CSNK2A2 (0.57)	PKMCSNK2A2CSNK2BCSNK2A1CAMK2B
	SCHEMBL18736360	0.89	TDP1 (0.48)	TDP1PKMCA12CA1CA2
	SCHEMBL18736482	0.89	GIGYF2 (0.53)	TDP1PKMMEN1ABL1LMNA
	SCHEMBL18705313	0.88	TDP1 (0.56)	TDP1PKMMEN1ABL1LMNA
	SCHEMBL24067621	0.88	ADORA2A (0.51)	TDP1PKMCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.