Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18705784 | 0.97 | ALDH1A1 (0.67) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL18706217 | 0.93 | ALDH1A1 (0.64) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL18705939 | 0.92 | ALDH1A1 (0.63) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL18706092 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL18706023 | 0.87 | ALDH1A1 (0.70) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL20768779 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL18706389 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL18706383 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL18705800 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HTTLMNAMAPTKMT2A | |
| SCHEMBL18705841 | 0.85 | SMYD3 (0.74) | ALDH1A1HTTLMNAKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371151-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | Agency For Science, Technology And Research (SG) | 2018-09-12 | — | — | EP | disclosed |
| WO-2017061957-A1 | COMPOUNDS FOR TREATMENT OF CANCER AND EPIGENETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-04-13 | — | — | WO | disclosed |