Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 14/20 | 1.00 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 1.00 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275557 | 1.00 | SIRT1 (1.00) | SIRT1SIRT2SIRT3RECQLALOX15 | |
| SCHEMBL1874310 | 1.00 | SIRT1 (1.00) | SIRT1SIRT2SIRT3RECQLALOX15 | |
| SCHEMBL8251110 | 0.96 | SIRT1 (1.00) | SIRT1SIRT2SIRT3RECQLALOX15 | |
| SCHEMBL8257650 | 0.96 | SIRT1 (1.00) | SIRT1SIRT2SIRT3RECQLALOX15 | |
| SCHEMBL1873844 | 0.96 | SIRT1 (1.00) | SIRT1SIRT2SIRT3RECQLALOX15 | |
| SCHEMBL3484154 | 0.92 | SIRT1 (1.00) | SIRT1SIRT2SIRT3RECQLALOX15 | |
| SCHEMBL1674922 | 0.88 | SIRT1 (0.79) | SIRT1SIRT2SIRT3ALOX15MEN1 | |
| SCHEMBL12989489 | 0.87 | SIRT1 (0.77) | SIRT1SIRT2SIRT3RECQLALOX15 | |
| SCHEMBL12990011 | 0.87 | SIRT1 (0.77) | SIRT1SIRT2SIRT3RECQLALOX15 | |
| SCHEMBL15353959 | 0.86 | MEN1 (0.77) | SIRT1SIRT2SIRT3RECQLALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140722-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF HEART FAILURE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-05-24 | — | — | US | claimed |
| EP-4746408-A2 | IMAGE CODING METHOD, IMAGE DECODING METHOD, MEMORY MANAGING METHOD, IMAGE CODING APPARATUS, IMAGE DECODING APPARATUS, MEMORY MANAGING APPARATUS, AND IMAGE CODING AND DECODING APPARATUS | Sun Patent Trust (US) | 2026-05-20 | — | — | EP | disclosed |
| CN-115955853-B | Organic light emitting diode and organic light emitting device including the same | 乐金显示有限公司 | 2026-05-15 | — | — | CN | disclosed |
| EP-4465629-B1 | IMAGE CODING AND DECODING | SUN PATENT TRUST (US) | 2026-05-13 | — | — | EP | disclosed |
| EP-3723754-B1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| EP-4734515-A2 | IMAGE ENCODING METHOD, IMAGE DECODING METHOD, IMAGE ENCODING DEVICE, IMAGE DECODING DEVICE, AND IMAGE CODING-DECODING DEVICE | Sun Patent Trust (US) | 2026-04-29 | — | — | EP | disclosed |
| EP-2822277-B1 | IMAGE CODING METHOD, IMAGE DECODING METHOD, IMAGE CODING DEVICE, IMAGE DECODING DEVICE, AND IMAGE CODING-DECODING DEVICE | SUN PATENT TRUST (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4729510-A1 | INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Suzhou Merna Therapeutics Co. Ltd (CN) | 2026-04-22 | — | — | EP | disclosed |
| EP-4730804-A2 | VIDEO DECODING METHOD, VIDEO DECODING DEVICE | Sun Patent Trust (US) | 2026-04-22 | — | — | EP | disclosed |
| US-12610069-B2 | Image decoding method, image coding method, image decoding apparatus, image coding apparatus, and image coding and decoding apparatus | SUN PATENT TRUST (US) | 2026-04-21 | — | — | US | disclosed |
| US-20090022694-A1 | SIRT1 INHIBITION | ELIXIR PHARMACEUTICALS, INC. | 2009-01-22 | — | — | US | disclosed |
| US-20090022694-A1 | SIRT1 INHIBITION | ELIXIR PHARMACEUTICALS, INC. | 2009-01-22 | — | — | US | disclosed |
| US-20080214800-A1 | Deacetylase which uses NAD as a cofactor; treating sirtuin related disorders | ELIXIR PHARMACEUTICALS, INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080214800-A1 | Deacetylase which uses NAD as a cofactor; treating sirtuin related disorders | ELIXIR PHARMACEUTICALS, INC. | 2008-09-04 | — | — | US | disclosed |
| WO-2008082646-A2 | HISTONE DEACETYLASE INHIBITORS, COMBINATION THERAPIES AND METHODS OF USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2008-07-10 | — | — | WO | disclosed |
| EP-1891949-A1 | Use of tricyclic indole derivatives for the treatment of muscular atrophy | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2008-02-27 | — | — | EP | disclosed |
| WO-2008019825-A1 | USE OF TRICYCLIC INDOLE DERIVATIVES FOR THE TREATMENT OF MUSCULAR DISEASES | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007047604-A2 | SIRT1 INHIBITION | ELIXIR PHARMACEUTICALS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
| WO-2006031894-A2 | METHODS OF TREATING A DISORDER | ELIXIR PHARMACEUTICALS, INC. (US) | 2006-03-23 | — | — | WO | disclosed |
| WO-2005026112-A2 | METHODS OF TREATING A DISORDER | ELIXIR PHARMACEUTICALS, INC. (US) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12610069-B2 | Image decoding method, image coding method, image decoding apparatus, image coding apparatus, and image coding and decoding apparatus | CBFB, CHRNA10, MYBBP1A | SIRT1 4456/4885SIRT2 4538/4885SIRT3 4600/4885 |
| US-20080214800-A1 | Deacetylase which uses NAD as a cofactor; treating sirtuin related disorders | SIRT3, SIRT1, SIRT2 | SIRT1 2/4885SIRT2 3/4885SIRT3 1/4885 |
| US-20090022694-A1 | SIRT1 INHIBITION | SIRT1, SIRT2, SIRT3 | SIRT1 1/4885SIRT2 2/4885SIRT3 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.