Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186607 | 0.75 | CCR4 (0.40) | CCR4 | |
| SCHEMBL185525 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL186109 | 0.73 | CCR4 (0.62) | CCR4 | |
| SCHEMBL10278999 | 0.72 | CCR4 (0.36) | CCR4 | |
| SCHEMBL186304 | 0.72 | CCR4 (0.44) | CCR4 | |
| SCHEMBL13241494 | 0.72 | CCR4 (0.44) | CCR4 | |
| SCHEMBL15310449 | 0.71 | CCR4 (0.65) | CCR4 | |
| SCHEMBL10234857 | 0.70 | CCR4 (0.61) | CCR4 | |
| SCHEMBL356727 | 0.67 | MAP2K1 (0.43) | CCR4 | |
| SCHEMBL1980737 | 0.66 | SCN9A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401270-A1 | PYRAZOLE DERIVATIVES USED AS CCR4 RECEPTOR ANTAGONISTS | Glaxo Group Limited (GB) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097395-A1 | PYRAZOLE DERIVATIVES USED AS CCR4 RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-09-02 | — | — | WO | disclosed |