SCHEMBL18708707

SCHEMBL18708707

COc1ccc(-c2ccc(-c3ccc(Oc4ccc(-c5ccc(-c6ccc(C)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.71
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
KMT2A Q03164 2/20 0.57
LTA4H P09960 2/20 0.56
RELA Q04206 1/20 0.56
TEAD4 Q15561 1/20 0.54
ESR2 Q92731 1/20 0.54
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
MAPT P10636 2/20 0.52
ALDH1A1 P00352 2/20 0.52
POLB P06746 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12334996 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL12761860 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL12276818 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL10044180 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL12334794 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL12335539 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL14826485 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL12770835 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL12770837 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H
SCHEMBL18656376 1.00 ACHE (0.71) ACHENPC1RAB9AKMT2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9868825-B2 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-01-16 US disclosed
US-9611361-B2 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-04-04 US disclosed