Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.60 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.60 |
| ▸ | MTOR | P42345 | 3/20 | 0.60 |
| ▸ | ABL1 | P00519 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 1/20 | 0.60 |
| ▸ | PRKDC | P78527 | 1/20 | 0.60 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | STK16 | O75716 | 1/20 | 0.51 |
| ▸ | STK10 | O94804 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
| ▸ | DCK | P27707 | 1/20 | 0.51 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884217 | 0.94 | PIK3CD (0.68) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL15582705 | 0.92 | PIK3CD (0.66) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL18709018 | 0.91 | PIK3CD (0.65) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL9884295 | 0.89 | PIK3CD (0.68) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL9884299 | 0.89 | PIK3CD (0.64) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL9884218 | 0.87 | PIK3CD (0.71) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL9924613 | 0.87 | PIK3CG (0.76) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL13781706 | 0.87 | PIK3CG (0.76) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL9883994 | 0.87 | PIK3CG (0.61) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR | |
| SCHEMBL19418809 | 0.86 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3CAPIK3CBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150609-A1 | PROCESS FOR PREPARING CERTAIN CHEMICAL ENTITIES | Intellikine, LLC (US) | 2017-04-05 | — | — | EP | disclosed |