Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868193 | 0.93 | BRAF (0.37) | BRAFCHRNA7 | |
| SCHEMBL1871027 | 0.92 | BRAF (0.31) | BRAF | |
| SCHEMBL1872280 | 0.84 | EGFR (0.38) | BRAF | |
| SCHEMBL1871231 | 0.83 | MAPK14 (0.35) | BRAF | |
| SCHEMBL1876309 | 0.83 | — | — | |
| SCHEMBL1873171 | 0.80 | PIK3CD (0.34) | — | |
| SCHEMBL12669715 | 0.79 | BRAF (0.44) | BRAF | |
| SCHEMBL1872187 | 0.77 | BRAF (0.49) | BRAF | |
| SCHEMBL12669162 | 0.76 | BRAF (0.47) | BRAF | |
| SCHEMBL1866612 | 0.76 | BRAF (0.42) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2498608-A1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | GlaxoSmithKline LLC (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011059610-A1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-05-19 | — | — | WO | disclosed |