Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25845385 | 0.91 | TLR2 (0.54) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL463455 | 0.91 | TLR2 (0.50) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL30973621 | 0.91 | TLR2 (0.50) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL12231705 | 0.91 | TLR2 (0.50) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL23447188 | 0.89 | TLR2 (0.56) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL23927996 | 0.88 | TLR2 (0.49) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL23927994 | 0.88 | TLR2 (0.49) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL15706351 | 0.88 | TLR2 (0.50) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL16048760 | 0.87 | TLR2 (0.51) | TLR2KMT2AMDM4TP53MDM2 | |
| SCHEMBL16048758 | 0.87 | TLR2 (0.51) | TLR2KMT2AMDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396040-B1 | USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION | GUERBET SA (FR) | 2017-04-05 | — | — | EP | disclosed |