SCHEMBL187098

SCHEMBL187098

N#CC1=C(C#N)C(=O)c2ccccc2C1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
CDC25B P30305 2/20 0.55
USP8 P40818 4/20 0.54
USP7 Q93009 3/20 0.54
KDM4E B2RXH2 3/20 0.52
POLB P06746 3/20 0.52
MAPT P10636 3/20 0.52
APAF1 O14727 2/20 0.52
TDP2 O95551 2/20 0.52
LMNA P02545 2/20 0.52
S100A4 P26447 2/20 0.52
RAB9A P51151 2/20 0.52
BLM P54132 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
CES2 O00748 1/20 0.52
TERT O14746 1/20 0.52
NPC1 O15118 1/20 0.52
PLIN1 O60240 1/20 0.52
S1PR4 O95977 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496222 1.00 MEN1 (0.55) MEN1KMT2ACDC25BUSP8USP7
SCHEMBL28383679 0.95 USP8 (0.50) MEN1KMT2ACDC25BUSP8USP7
Aniline SCHEMBL10935922 0.87 USP8 (0.44) MEN1KMT2ACDC25BUSP8USP7
SCHEMBL29045145 0.84 USP8 (0.46) MEN1KMT2ACDC25BUSP8USP7
SCHEMBL28931700 0.84 USP8 (0.46) MEN1KMT2ACDC25BUSP8USP7
SCHEMBL27288189 0.81 CA1 (0.47) USP8USP7RAB9ANPC1MAPK1
SCHEMBL10967500 0.81 ALDH1A1 (0.50) MEN1KMT2ACDC25BUSP8USP7
SCHEMBL15765937 0.78 ALDH1A1 (0.43) MEN1KMT2ACDC25BUSP8USP7
Anthraquinone SCHEMBL27537802 0.78 MEN1 (0.71) MEN1KMT2ACDC25BUSP8USP7
SCHEMBL12015510 0.77 NR1H3 (0.41) MEN1KMT2AUSP8USP7POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018219574-A1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS HENKEL AG & CO. KGAA (DE) 2018-12-06 WO claimed
EP-3409707-A1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS Henkel AG & Co. KGaA (DE) 2018-12-05 EP claimed
EP-0436921-B1 Inhibitor concentrate, storage stable unsaturated thermosettable resins and cured products DOW CHEMICAL CO (US) 1997-03-12 EP claimed
EP-0350709-B1 Organic conductive complex SUMITOMO ELECTRIC INDUSTRIES (JP) 1994-09-21 EP claimed
US-5030387-A Anthraquinone derivatives SUMITOMO ELECTRIC INDUSTRIES LTD. (JP) 1991-07-09 US claimed
EP-0350709-A2 Organic conductive complex SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1990-01-17 EP claimed
JP-5019316-A None JP disclosed
JP-63085749-A None JP disclosed
JP-58224793-A None JP disclosed
JP-59076296-A None JP disclosed
JP-59131493-A None JP disclosed
JP-59048187-A None JP disclosed
JP-63221086-A None JP disclosed
JP-S59131494-A OPTICAL RECORDING SYSTEM NEC CORP 1984-07-28 JP disclosed
JP-S5976296-A PREPARATION OF OPTICAL RECORDING MEDIUM NEC CORP 1984-05-01 JP disclosed
JP-S5976297-A OPTICAL RECORDING SYSTEM NEC CORP 1984-05-01 JP disclosed
JP-S5948187-A PHOTO RECORDING MEDIUM NEC CORP 1984-03-19 JP disclosed
JP-S58224793-A OPTICAL RECORDING MEDIUM NEC CORP 1983-12-27 JP disclosed
US-4398753-A METHINE-TYPE DYES AND QUINONE DERIVATIVE IN REDOX SYSTEM FOR CARBON-FREE REPRODUCTION MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1983-08-16 US disclosed
EP-0055847-A1 Pressure sensitive recording unit MITSUI TOATSU CHEMICALS, Inc. (JP) 1982-07-14 EP disclosed