Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612535 | 0.78 | KDM4E (0.43) | LMNAALDH1A1KDM4EL3MBTL1USP2 | |
| SCHEMBL21414346 | 0.77 | KDM4E (0.41) | LMNAALDH1A1GAAKDM4EL3MBTL1 | |
| SCHEMBL13822511 | 0.74 | — | — | |
| SCHEMBL20780310 | 0.74 | LMNA (0.38) | LMNAALDH1A1GAAKDM4EL3MBTL1 | |
| SCHEMBL1874567 | 0.71 | HRH3 (0.45) | LMNAALDH1A1GAAKDM4EUSP2 | |
| SCHEMBL29276470 | 0.71 | LMNA (0.36) | LMNAALDH1A1GAAKDM4EL3MBTL1 | |
| SCHEMBL28104621 | 0.70 | LMNA (0.43) | LMNAALDH1A1GAAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2947548 | 0.70 | HRH3 (0.44) | LMNAALDH1A1KDM4EUSP2HPGD | |
| SCHEMBL741443 | 0.70 | HRH3 (0.44) | LMNAALDH1A1GAAKDM4EUSP2 | |
| SCHEMBL28785125 | 0.70 | HRH3 (0.44) | LMNAALDH1A1GAAKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660010-A1 | S1P MODULATING AGENTS | Biogen MA Inc. (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3150590-A1 | S1P MODULATING AGENTS | Biogen MA Inc. (US) | 2017-04-05 | — | — | EP | disclosed |