Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 13/20 | 0.55 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.54 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186852 | 0.78 | HDAC3 (0.40) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL3860550 | 0.78 | KCNN4 (0.46) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL28151671 | 0.78 | KCNN4 (0.68) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL14663469 | 0.77 | KMT2A (0.43) | KCNN4KCNE1KCNQ1KMT2ACHRM3 | |
| SCHEMBL2781433 | 0.77 | MAPT (0.68) | KCNN4MAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL28589452 | 0.77 | MAPT (0.53) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL4447301 | 0.76 | KMT2A (0.49) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL27347246 | 0.76 | KMT2A (0.49) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL29096654 | 0.75 | MAPT (0.65) | KCNN4MAPTKMT2AHDAC3HDAC4 | |
| Bromomethane SCHEMBL3192554 | 0.75 | CYP2C9 (0.46) | KCNN4KCNE1KCNQ1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051243-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |