Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 14/20 | 0.68 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.57 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781433 | 0.88 | MAPT (0.68) | KCNN4MAPTKMT2AHDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL29096654 | 0.86 | MAPT (0.65) | KCNN4MAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL4800452 | 0.83 | MAPT (0.57) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL2337394 | 0.81 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL28875440 | 0.81 | KCNN4 (0.72) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| Senicapoc SCHEMBL1443805 | 0.81 | KCNN4 (1.00) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL1871077 | 0.78 | KCNN4 (0.55) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL7694323 | 0.78 | NPC1 (0.48) | KCNN4KCNE1KCNQ1MAPTKMT2A | |
| SCHEMBL2202450 | 0.78 | KMT2A (0.55) | KCNN4MAPTKMT2AHDAC3HDAC4 | |
| SCHEMBL5056595 | 0.78 | KCNN4 (0.68) | KCNN4KCNE1KCNQ1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603136-B | Process for preparing substituted triazolopyridines | 拜耳医药股份有限公司 | 2017-06-27 | — | — | CN | disclosed |