Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702804 | 0.90 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1811037 | 0.84 | BCL2 (0.90) | BCL2 | |
| SCHEMBL1701578 | 0.83 | BCL2 (0.70) | BCL2 | |
| SCHEMBL1868297 | 0.83 | BCL2 (0.81) | BCL2 | |
| SCHEMBL1869790 | 0.82 | BCL2 (0.84) | BCL2 | |
| SCHEMBL19424395 | 0.82 | BCL2 (0.82) | BCL2 | |
| SCHEMBL1701823 | 0.82 | BCL2 (0.68) | BCL2 | |
| SCHEMBL30313845 | 0.81 | BCL2 (0.82) | BCL2 | |
| SCHEMBL1701414 | 0.81 | BCL2 (0.82) | BCL2 | |
| SCHEMBL1869170 | 0.78 | BCL2 (0.82) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435432-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2012-04-04 | — | — | EP | disclosed |
| WO-2010138588-A9 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | disclosed |
| WO-2010138588-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-12-02 | — | — | WO | disclosed |