Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103368 | 0.83 | ABCB1 (0.40) | GLAKDM4E | |
| SCHEMBL15149266 | 0.83 | ALDH1A1 (0.55) | GLAKDM4E | |
| Cridanimod SCHEMBL3372087 | 0.75 | GLA (1.00) | GLAKDM4EMEN1CASP1CASP7 | |
| Cridanimod SCHEMBL29373385 | 0.75 | GLA (1.00) | GLAKDM4EMEN1CASP1CASP7 | |
| Cridanimod SCHEMBL3801665 | 0.75 | GLA (1.00) | GLAKDM4EMEN1CASP1CASP7 | |
| Cridanimod SCHEMBL3375823 | 0.74 | GLA (0.96) | GLAKDM4EMEN1CASP1CASP7 | |
| Cridanimod SCHEMBL3375819 | 0.74 | GLA (0.96) | GLAKDM4EMEN1CASP1CASP7 | |
| Cridanimod SCHEMBL27895128 | 0.74 | GLA (0.96) | GLAKDM4EMEN1CASP1CASP7 | |
| SCHEMBL19393423 | 0.72 | P2RX4 (0.40) | — | |
| SCHEMBL26407841 | 0.71 | KDM4E (0.47) | KDM4EMEN1CASP1CASP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190300947-A1 | DNA SEQUENCING BY NANOPORE USING MODIFIED NUCLEOTIDES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-10-03 | — | — | US | disclosed |
| US-20170096704-A1 | DNA SEQUENCING BY NANOPORE USING MODIFIED NUCLEOTIDES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-04-06 | — | — | US | disclosed |