SCHEMBL187153

SCHEMBL187153

COc1c(O)ccc(C=CC(=O)O)c1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA4 P22748 3/20 0.51
PKM P14618 2/20 0.51
CA12 O43570 2/20 0.51
CA3 P07451 2/20 0.51
CA6 P23280 2/20 0.51
CA5A P35218 2/20 0.51
CA7 P43166 2/20 0.51
CA9 Q16790 2/20 0.51
CA14 Q9ULX7 2/20 0.51
CA5B Q9Y2D0 2/20 0.51
CSNK2A2 P19784 1/20 0.51
SNCA P37840 1/20 0.51
CSNK2B P67870 1/20 0.51
CSNK2A1 P68400 1/20 0.51
CSNK2A3 Q8NEV1 1/20 0.51
ABCG2 Q9UNQ0 1/20 0.50
NFKB1 P19838 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187151 1.00 KDM4E (0.51) KDM4ECA1CA2CA4PKM
SCHEMBL6852627 0.91 ABCG2 (0.57) KDM4ECA1CA2CA4PKM
SCHEMBL6852630 0.91 ABCG2 (0.57) KDM4ECA1CA2CA4PKM
SCHEMBL21317660 0.88 KDM4E (0.50) KDM4ECA1CA2CA4PKM
SCHEMBL6655468 0.88 KDM4E (0.50) KDM4ECA1CA2CA4PKM
SCHEMBL21317659 0.88 KDM4E (0.50) KDM4ECA1CA2CA4PKM
SCHEMBL2535572 0.87 KDM4E (0.49) KDM4ECA1CA2CA4PKM
SCHEMBL10875625 0.87 KDM4E (0.49) KDM4ECA1CA2CA4PKM
SCHEMBL10445525 0.85 CA1 (0.62) KDM4ECA1CA2CA4PKM
SCHEMBL10445523 0.85 CA1 (0.62) KDM4ECA1CA2CA4PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109010101-A A kind of phosphoramidite chemical sun-screening agent and wide spectrum suncream and preparation method thereof 天津大学 2018-12-18 CN claimed
EP-3183553-A1 METHOD OF SAMPLE PREPARATION FOR MALDI AND AUTOMATED SYSTEM THEREFOR Becton, Dickinson and Company (US) 2017-06-28 EP claimed
US-20160379811-A1 METHOD OF DETERMINING CELL CYCLE STAGE DISTRIBUTION OF CELLS CITY UNIVERSITY OF HONG KONG (HK) 2016-12-29 US claimed
WO-2016028684-A1 METHOD OF SAMPLE PREPARATION FOR MALDI AND AUTOMATED SYSTEM THEREFOR BECTON, DICKINSON AND COMPANY (US) 2016-02-25 WO claimed
US-8653326-B2 Targeted DNA insertion in plants BAYER CROPSCIENCE N.V. (BE) 2014-02-18 US claimed
US-20100003759-A1 TARGETED DNA INSERTION IN PLANTS BAYER BIOSCIENCE N.V. (BE) 2010-01-07 US claimed
US-7598365-B2 Targeted DNA insertion in plants BAYER BIOSCIENCE N.V. (BE) 2009-10-06 US claimed
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP claimed
EP-1689870-A2 IMPROVED TARGETED DNA INSERTION IN PLANTS Bayer BioScience N.V. (BE) 2006-08-16 EP claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
WO-2005049842-A2 IMPROVED TARGETED DNA INSERTION IN PLANTS BAYER BIOSCIENCE N.V. (BE) 2005-06-02 WO claimed
EP-0491706-A1 METHOD OF PREPARING A SAMPLE FOR ANALYSIS. FINNIGAN MAT LTD (GB) 1992-07-01 EP claimed
WO-1991004570-A1 METHOD OF PREPARING A SAMPLE FOR ANALYSIS FINNIGAN MAT LTD. (GB) 1991-04-04 WO claimed
WO-2024125597-A1 COMPOSITIONS AND METHODS FOR INFECTIOUS DISEASES PROVIDENCE THERAPEUTICS HOLDINGS INC. (CA) 2024-06-20 WO disclosed
CN-117586986-A Compositions and methods comprising lipolytic enzyme variants 丹尼斯科美国公司 2024-02-23 CN disclosed
CN-110093330-B Compositions and methods comprising lipolytic enzyme variants 丹尼斯科美国公司 2023-11-28 CN disclosed
WO-1998001519-A1 PROCESS FOR OBTAINING ORYZANOL UNILEVER N.V. (NL) 1998-01-15 WO disclosed
CN-1165033-A Isolation of novel peptides from green barley leaf extract and use of same to inhibit human platelet aggregation HAGIWARA YOSHIHIDE (JP) 1997-11-19 CN disclosed
EP-0782581-A1 CLONING OF AN INSULIN-DEPENDENT MEMBRANE AMINOPEPTIDASE FROM GLUT-4 VESICLES Bayer Corporation (US) 1997-07-09 EP disclosed
WO-1996009317-A1 CLONING OF AN INSULIN-DEPENDENT MEMBRANE AMINOPEPTIDASE FROM GLUT-4 VESICLES BAYER CORPORATION (US) 1996-03-28 WO disclosed