Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195106 | 0.89 | MDM4 (0.46) | MDM4TP53MDM2CASP3 | |
| SCHEMBL16278331 | 0.89 | MDM4 (0.46) | MDM4TP53MDM2CASP3 | |
| SCHEMBL15067200 | 0.89 | MDM4 (0.46) | MDM4TP53MDM2CASP3 | |
| Trifluoroacetic Acid SCHEMBL31494720 | 0.86 | MDM4 (0.43) | MDM4TP53MDM2CASP3 | |
| Trifluoroacetic Acid SCHEMBL29125245 | 0.86 | MDM4 (0.43) | MDM4TP53MDM2CASP3 | |
| SCHEMBL30195131 | 0.80 | PTPN1 (0.44) | MDM4TP53MDM2CASP3 | |
| SCHEMBL29125239 | 0.79 | MDM4 (0.40) | MDM4TP53MDM2CASP3 | |
| SCHEMBL1405816 | 0.77 | MDM4 (0.54) | MDM4TP53MDM2CASP3 | |
| SCHEMBL1486208 | 0.77 | MDM4 (0.54) | MDM4TP53MDM2CASP3 | |
| SCHEMBL29399772 | 0.77 | MDM4 (0.54) | MDM4TP53MDM2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096450-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | NOVO NORDISK AS (DK) | 2017-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170096450-A1 | Dipeptide Comprising a Non-Proteogenic Amino Acid | DNPEP, ANPEP, NPEPPS | MDM4 431/4885TP53 181/4885MDM2 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.