Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.92 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lupinine SCHEMBL2633852 | 0.96 | TDP1 (1.00) | TDP1TSHRHTT | |
| Lupinine SCHEMBL177708 | 0.96 | TDP1 (1.00) | TDP1TSHRHTT | |
| Lupinine SCHEMBL914675 | 0.96 | TDP1 (1.00) | TDP1TSHRHTT | |
| Lupinine SCHEMBL13593464 | 0.96 | TDP1 (1.00) | TDP1TSHRHTT | |
| SCHEMBL9040301 | 0.91 | TDP1 (0.84) | TDP1SLC18A3 | |
| SCHEMBL31501784 | 0.91 | TDP1 (0.91) | TDP1TSHRHTT | |
| SCHEMBL16757274 | 0.91 | TDP1 (0.91) | TDP1TSHRHTT | |
| Lupinine SCHEMBL13735902 | 0.85 | TDP1 (0.79) | TDP1TSHRHTT | |
| SCHEMBL23043270 | 0.84 | TDP1 (0.80) | TDP1SLC18A3 | |
| SCHEMBL19317460 | 0.84 | TDP1 (0.80) | TDP1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006794-A9 | 3-OXO-2, 3-DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDES AS PARP INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2011-05-05 | — | — | WO | disclosed |