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SCHEMBL18716882

SCHEMBL18716882

CC(=O)NC1CCC(=O)NCCCC(C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C(Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TSLP Q969D9 16/20 0.59
▸ MC4R P32245 4/20 0.58
▸ MC3R P41968 2/20 0.58
▸ MC5R P33032 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7855681 1.00 TSLP (0.59) TSLPMC4RMC3RMC5R
SCHEMBL16340639 0.96 MC4R (0.57) TSLPMC4RMC3R
SCHEMBL18716894 0.95 MC4R (0.56) TSLPMC4RMC3RMC5R
SCHEMBL18716875 0.92 MC4R (0.67) TSLPMC4RMC3RMC5R
SCHEMBL19473935 0.92 MC4R (0.67) TSLPMC4RMC3RMC5R
SCHEMBL18716895 0.92 MC4R (0.67) TSLPMC4RMC3RMC5R
SCHEMBL7856766 0.92 MC4R (0.67) TSLPMC4RMC3RMC5R
SCHEMBL14271537 0.92 MC3R (0.62) TSLPMC4RMC3RMC5R
SCHEMBL18716876 0.92 MC4R (0.56) TSLPMC4RMC3RMC5R
SCHEMBL18717187 0.92 MC4R (0.59) TSLPMC4RMC3RMC5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440572-B1 LACTAM-BRIDGED MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES PALATIN TECHNOLOGIES INC (US) 2017-04-05 — — EP disclosed
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