Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18717305 | 0.79 | ERN1 (0.70) | ERN1 | |
| SCHEMBL12767144 | 0.78 | ERN1 (0.80) | ERN1 | |
| SCHEMBL13639937 | 0.78 | ERN1 (0.76) | ERN1 | |
| SCHEMBL29946536 | 0.76 | ERN1 (0.58) | ERN1 | |
| SCHEMBL13018748 | 0.75 | ERN1 (0.71) | ERN1 | |
| SCHEMBL12767143 | 0.75 | ERN1 (0.71) | ERN1 | |
| SCHEMBL12767138 | 0.74 | ERN1 (1.00) | ERN1 | |
| SCHEMBL12767147 | 0.74 | ERN1 (1.00) | ERN1 | |
| SCHEMBL12767133 | 0.73 | ERN1 (1.00) | ERN1 | |
| SCHEMBL18717103 | 0.73 | ERN1 (0.77) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150589-A1 | IRE-1A INHIBITORS | MannKind Corporation (US) | 2017-04-05 | — | — | EP | disclosed |