Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 19/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22750626 | 0.77 | ERN1 (0.65) | ERN1 | |
| SCHEMBL18717318 | 0.76 | ERN1 (0.59) | ERN1 | |
| SCHEMBL30393816 | 0.76 | ERN1 (0.69) | ERN1 | |
| SCHEMBL3905421 | 0.76 | ERN1 (0.69) | ERN1 | |
| SCHEMBL28800880 | 0.75 | ERN1 (0.67) | ERN1 | |
| SCHEMBL12675169 | 0.73 | ERN1 (0.65) | ERN1 | |
| SCHEMBL9446315 | 0.73 | ERN1 (0.65) | ERN1 | |
| SCHEMBL1414921 | 0.73 | ERN1 (1.00) | ERN1 | |
| SCHEMBL4010301 | 0.73 | ERN1 (0.59) | ERN1 | |
| SCHEMBL22750630 | 0.73 | ERN1 (0.62) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220304958-A1 | SMALL MOLECULE INHIBITORS OF A PROTEIN COMPLEX | SERBP1, PPHLN1, VCAM1 | ERN1 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.