Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.54 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18732837 | 1.00 | TYR (0.74) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL18718085 | 1.00 | TYR (0.74) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL21334201 | 1.00 | TYR (0.74) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL18732839 | 1.00 | TYR (0.74) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL18732835 | 1.00 | TYR (0.74) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL21334202 | 1.00 | TYR (0.74) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL23758910 | 0.92 | TYR (0.64) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL21334204 | 0.92 | TYR (0.64) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL18733424 | 0.92 | TYR (0.64) | TYRPOLBNPC1RAB9ASLC5A2 | |
| SCHEMBL18718089 | 0.92 | TYR (0.64) | TYRPOLBNPC1RAB9ASLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170102349-A1 | ELECTROCHEMICAL METHODS AND COMPOUNDS FOR THE DETECTION OF ENZYMES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170102349-A1 | ELECTROCHEMICAL METHODS AND COMPOUNDS FOR THE DETECTION OF ENZYMES | EPX, DNASE1, DERA | TYR 646/4885POLB 101/4885NPC1 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.