Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.51 |
| ▸ | CA2 | P00918 | 10/20 | 0.51 |
| ▸ | CA9 | Q16790 | 10/20 | 0.51 |
| ▸ | CA12 | O43570 | 6/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.45 |
| ▸ | ELF3 | P78545 | 3/20 | 0.45 |
| ▸ | MED23 | Q9ULK4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15216663 | 1.00 | CA1 (0.51) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15216676 | 0.99 | CA1 (0.51) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15216686 | 0.95 | CA12 (0.44) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15218363 | 0.94 | CA1 (0.50) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15218283 | 0.93 | CA1 (0.50) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15216670 | 0.93 | CA1 (0.49) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15216690 | 0.88 | HTR3A (0.43) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15218282 | 0.87 | CA1 (0.48) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15216675 | 0.86 | HDAC3 (0.48) | CA1CA2CA9CA12HTR3A | |
| SCHEMBL15216667 | 0.85 | CA1 (0.50) | CA1CA2CA9CA12HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9874562-B2 | Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses | ACADEMIA SINICA (TW) | 2018-01-23 | — | — | US | disclosed |
| US-20170102387-A1 | ZANAMIVIR PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY AND DETERMINING OSELTAMIVIR SUSCEPTIBILITY OF INFLUENZA VIRUSES | ACADEMIA SINICA (TW) | 2017-04-13 | — | — | US | disclosed |