Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | FES | P07332 | 2/20 | 0.44 |
| ▸ | ROS1 | P08922 | 2/20 | 0.44 |
| ▸ | FER | P16591 | 2/20 | 0.44 |
| ▸ | FLT4 | P35916 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.44 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.44 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.44 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1869906 | 1.00 | MASP2 (0.44) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1874525 | 0.93 | MASP2 (0.43) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1874535 | 0.93 | MASP2 (0.43) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1875523 | 0.93 | MASP2 (0.43) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1875531 | 0.93 | MASP2 (0.43) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1872344 | 0.90 | MASP2 (0.44) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1872338 | 0.90 | MASP2 (0.44) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1873100 | 0.90 | MASP2 (0.44) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1873107 | 0.90 | MASP2 (0.44) | MASP2MAP4K4CHEK2CDK1FES | |
| SCHEMBL1873380 | 0.89 | MASP2 (0.43) | MASP2MAP4K4CHEK2CDK1FES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |