Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30144812 | 0.90 | KDM4E (0.42) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL595630 | 0.90 | KDM4E (0.42) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL25356663 | 0.82 | KDM4E (0.51) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9154255 | 0.81 | KDM1A (0.36) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL9154250 | 0.81 | KDM1A (0.36) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL18722125 | 0.80 | ESR2 (0.45) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL9158730 | 0.80 | SPHK1 (0.38) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL9158726 | 0.80 | SPHK1 (0.38) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL15448506 | 0.79 | ESR2 (0.50) | ESR2KDM4EGLAHTTKMT2A | |
| SCHEMBL13085544 | 0.79 | QDPR (0.47) | KDM1AMAOAMAOBSPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |