Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14569984 | 0.88 | KMT2A (0.49) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL27304019 | 0.83 | KMT2A (0.47) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL27306231 | 0.81 | KMT2A (0.53) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL7907183 | 0.81 | KMT2A (0.48) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL7907189 | 0.81 | KMT2A (0.48) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL19185924 | 0.80 | KMT2A (0.51) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL28589485 | 0.80 | KMT2A (0.59) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL10574401 | 0.80 | KMT2A (0.88) | KMT2AHTTSMN1; SMN2TDP1POLB | |
| SCHEMBL27480734 | 0.80 | KMT2A (0.44) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL16349701 | 0.79 | KMT2A (0.42) | KMT2AHTTSMN1; SMN2TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| CN-1037334-A | Pyridine derivate | MERCK PATENT GMBH (DE) | 1989-11-22 | — | — | CN | disclosed |