Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907189 | 1.00 | KMT2A (0.48) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL7908294 | 0.93 | KMT2A (0.52) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL7908296 | 0.93 | KMT2A (0.52) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL27324727 | 0.91 | KMT2A (0.51) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL7910394 | 0.91 | KMT2A (0.51) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL30172 | 0.91 | KMT2A (0.51) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL27480734 | 0.91 | KMT2A (0.44) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL27301975 | 0.90 | KMT2A (0.50) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL27299978 | 0.90 | KMT2A (0.50) | KMT2AMAPTHTTSMN1; SMN2TDP1 | |
| SCHEMBL27306208 | 0.90 | KMT2A (0.50) | KMT2AMAPTHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210760-B1 | SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5387369-A | With specified mixture of components; short switching times | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-07 | — | — | US | disclosed |
| US-5286410-A | Positive dielectric anisotropy | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-02-15 | — | — | US | disclosed |
| CN-1037334-A | Pyridine derivate | MERCK PATENT GMBH (DE) | 1989-11-22 | — | — | CN | disclosed |