Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18818746 | 0.90 | PDK2 (0.38) | DUSP3PDK2ALKBH5FTOLMNA | |
| SCHEMBL20405267 | 0.90 | DUSP3 (0.37) | DUSP3PDK2ALKBH5FTOLMNA | |
| SCHEMBL13175596 | 0.87 | PDK2 (0.37) | DUSP3PDK2ALKBH5FTOLMNA | |
| SCHEMBL14666327 | 0.86 | DUSP3 (0.42) | DUSP3ALKBH5FTOLMNAMAPT | |
| SCHEMBL11992355 | 0.84 | DUSP3 (0.43) | DUSP3ALKBH5FTOLMNAMAPT | |
| SCHEMBL23362652 | 0.84 | DUSP3 (0.37) | DUSP3PDK2GAAKDM4EPARP1 | |
| SCHEMBL18821335 | 0.84 | DUSP3 (0.37) | DUSP3PDK2LMNAMAPTHTT | |
| SCHEMBL29461388 | 0.84 | DUSP3 (0.37) | DUSP3PDK2GAAKDM4EPARP1 | |
| SCHEMBL16596830 | 0.84 | DUSP3 (0.37) | DUSP3KDM4EATML3MBTL1 | |
| SCHEMBL18624225 | 0.83 | ALKBH5 (0.38) | DUSP3PDK2ALKBH5FTOLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617291-B2 | Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-04-11 | — | — | US | disclosed |