Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16522412 | 0.88 | SLC9A1 (0.43) | SLC9A1FAAHMGLLRAB9AUSP2 | |
| SCHEMBL16526236 | 0.83 | SLC9A1 (0.60) | SLC9A1FAAHMGLLALDH1A1LMNA | |
| SCHEMBL18723166 | 0.79 | SLC9A1 (0.43) | SLC9A1MGLLLMNAMEN1KMT2A | |
| SCHEMBL11959511 | 0.75 | SLC9A1 (0.68) | SLC9A1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL12672863 | 0.75 | SLC9A1 (0.55) | SLC9A1FAAHMGLLALDH1A1LMNA | |
| SCHEMBL13173782 | 0.74 | KDM1A (0.44) | SLC9A1FAAHMGLLALDH1A1LMNA | |
| SCHEMBL13780815 | 0.69 | SLC9A1 (0.66) | SLC9A1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL21297115 | 0.68 | SLC9A1 (0.39) | SLC9A1FAAHMGLLALDH1A1TUBB4A | |
| SCHEMBL24983450 | 0.68 | SLC9A1 (0.40) | SLC9A1FAAHMGLL | |
| SCHEMBL8256698 | 0.66 | SLC9A1 (0.50) | SLC9A1FAAHMGLLRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9616099-B2 | Cyclosporin analogues for preventing or treating hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2017-04-11 | — | — | US | disclosed |