SCHEMBL18723342

SCHEMBL18723342

Cc1cccc(C2(c3ccccc3)c3cc(Br)ccc3-c3ccc(Br)cc32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
MAPK1 P28482 1/20 0.44
NPSR1 Q6W5P4 3/20 0.40
LMNA P02545 1/20 0.40
PDK2 Q15119 3/20 0.39
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
OPRM1 P35372 2/20 0.35
OPRD1 P41143 2/20 0.35
HDAC4 P56524 1/20 0.33
ACHE P22303 1/20 0.33
BACE1 P56817 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
OPRK1 P41145 1/20 0.33
OPRL1 P41146 1/20 0.33
SORT1 Q99523 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15316155 0.95 MAPK1 (0.48) ALDH1A1MAPK1NPSR1LMNAPDK2
SCHEMBL12109715 0.90 PDK2 (0.41) ALDH1A1MAPK1NPSR1LMNAPDK2
SCHEMBL3852176 0.87 PDK2 (0.41) ALDH1A1MAPK1LMNAPDK2ESR1
SCHEMBL1307887 0.87 PDK2 (0.47) ALDH1A1MAPK1LMNAPDK2OPRM1
SCHEMBL29540116 0.87 PDK2 (0.47) ALDH1A1MAPK1LMNAPDK2OPRM1
SCHEMBL27905145 0.84 PDK2 (0.41) ALDH1A1MAPK1NPSR1LMNAPDK2
SCHEMBL12781954 0.83 ESR1 (0.45) ALDH1A1NPSR1LMNAPDK2ESR1
SCHEMBL21258346 0.83 NPSR1 (0.48) NPSR1LMNAPDK2ESR1ESR2
SCHEMBL28813511 0.83 ALDH1A1 (0.38) ALDH1A1MAPK1NPSR1LMNAPDK2
SCHEMBL1644538 0.83 ALDH1A1 (0.50) ALDH1A1MAPK1NPSR1LMNAPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793486-B2 Polymer compound and light-emitting element using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-9780308-B2 Composition and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-03 US disclosed
US-9620717-B2 Composition and block type copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-11 US disclosed