Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13397412 | 0.86 | ATM (0.41) | ATML3MBTL1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL15968423 | 0.79 | CD81 (0.32) | — | |
| SCHEMBL18723756 | 0.79 | CD81 (0.32) | — | |
| SCHEMBL18723626 | 0.79 | CD81 (0.32) | — | |
| SCHEMBL18723519 | 0.79 | CD81 (0.32) | TSHR | |
| SCHEMBL17317455 | 0.79 | ATM (0.48) | ATML3MBTL1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19226071 | 0.73 | ATM (0.36) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL19226275 | 0.73 | ATM (0.36) | ATML3MBTL1CYP1A2CYP2C9TSHR | |
| SCHEMBL25544492 | 0.72 | ATM (0.47) | ATML3MBTL1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL25544491 | 0.72 | ATM (0.47) | ATML3MBTL1CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066648-B1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | ESTEVE LABOR DR (ES) | 2017-04-12 | — | — | EP | disclosed |