SCHEMBL18723519

SCHEMBL18723519

CC1(C)C(CCO)CC1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CD81 P60033 1/20 0.32
APLNR P35414 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15968423 0.84 CD81 (0.32) CD81
SCHEMBL18723626 0.84 CD81 (0.32) CD81
SCHEMBL18723756 0.84 CD81 (0.32) CD81
SCHEMBL13397411 0.84 CD81 (0.32) CD81APLNRSLC1A2SLC1A1
SCHEMBL18723524 0.79 ATM (0.41) TSHR
SCHEMBL18526447 0.79 SLC1A2 (0.32) SLC1A2SLC1A1
SCHEMBL12946601 0.79 APLNR (0.33) CD81APLNRSLC1A2SLC1A1
SCHEMBL6152852 0.78 GRM2 (0.39) CD81APLNRSLC1A2SLC1A1
SCHEMBL13851453 0.78 GRM2 (0.39) CD81APLNRSLC1A2SLC1A1
SCHEMBL23826186 0.74 SLC1A2 (0.33) CD81APLNRSLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2066648-B1 SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS ESTEVE LABOR DR (ES) 2017-04-12 EP disclosed