Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406052 | 1.00 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL10029256 | 1.00 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL404321 | 0.86 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL10029225 | 0.86 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL18724481 | 0.86 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL10029236 | 0.85 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL18724092 | 0.85 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL404251 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL10029257 | 0.85 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL18691802 | 0.84 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638938-B1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ORTHOPOXVIRUS INFECTIONS AND ASSOCIATED DISEASES | SIGA TECH INC (US) | 2017-04-12 | — | — | EP | disclosed |