⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18727733 | 0.70 | — | — | |
| SCHEMBL10181957 | 0.66 | LMNA (0.31) | — | |
| SCHEMBL13370047 | 0.63 | — | — | |
| SCHEMBL20121853 | 0.61 | GAA (0.30) | — | |
| SCHEMBL23280210 | 0.61 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL7178297 | 0.58 | LMNA (0.31) | — | |
| SCHEMBL24827238 | 0.58 | — | — | |
| SCHEMBL22292613 | 0.55 | GAA (0.31) | — | |
| SCHEMBL4722960 | 0.54 | — | — | |
| SCHEMBL21814714 | 0.54 | LMNA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153023-A1 | BENZOXAZOLE KINASE INHIBITORS AND METHODS OF USE | Intellikine, LLC (US) | 2017-04-12 | — | — | EP | disclosed |