Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18729489 | 0.92 | LDHA (0.41) | LDHASMN1; SMN2ADORA1ADORA3ADORA2A | |
| SCHEMBL18729562 | 0.87 | LDHA (0.49) | LDHASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL18730284 | 0.83 | LDHA (0.46) | LDHASMN1; SMN2ADORA1ADORA3ADORA2A | |
| SCHEMBL18730297 | 0.83 | LDHA (0.50) | LDHASMN1; SMN2ADORA1ADORA3ADORA2A | |
| SCHEMBL18729551 | 0.81 | LDHA (0.44) | LDHASMN1; SMN2ADORA1ADORA2ANPC1 | |
| SCHEMBL18729501 | 0.81 | CYP1A2 (0.39) | SMN1; SMN2NPC1RAB9AKMT2ACYP3A4 | |
| SCHEMBL17637115 | 0.80 | ADORA1 (0.38) | LDHAADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL22391542 | 0.80 | ADORA1 (0.38) | LDHAADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL18729619 | 0.79 | LDHA (0.43) | LDHASMN1; SMN2ADORA1ADORA2ANPC1 | |
| SCHEMBL22087537 | 0.79 | ADORA1 (0.37) | LDHAADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159350-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2017-04-26 | — | — | EP | disclosed |
| EP-3001480-B1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORP (US) | 2017-04-12 | — | — | EP | disclosed |