Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859894 | 0.77 | KDM4E (0.55) | IDO1POLBCYP3A4MAPT | |
| SCHEMBL18731544 | 0.73 | IDO1 (0.51) | ASIC3IDO1POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL18730921 | 0.73 | IDO1 (0.51) | ASIC3IDO1POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL17800997 | 0.73 | IDO1 (0.75) | ASIC3IDO1POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL18731255 | 0.69 | IDO1 (0.46) | ASIC3IDO1POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL27880327 | 0.68 | IDO1 (0.67) | ASIC3IDO1POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL18731394 | 0.66 | IDO1 (0.38) | ASIC3IDO1POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL27577902 | 0.66 | IDO1 (0.91) | ASIC3IDO1POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL11211676 | 0.64 | HRH2 (0.32) | CYP2C19 | |
| SCHEMBL205481 | 0.63 | IDO1 (0.64) | ASIC3IDO1POLBSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513091-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-04-12 | — | — | EP | disclosed |