Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18730890 | 0.77 | ASIC3 (0.44) | CYP3A4MAPTIDO1POLB | |
| SCHEMBL7442855 | 0.77 | KDM4E (0.60) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| Bromide SCHEMBL10355410 | 0.75 | CYP3A4 (0.58) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| Hydrochloric Acid SCHEMBL7430812 | 0.75 | CYP3A4 (0.58) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| Hydrochloric Acid SCHEMBL10355391 | 0.75 | KDM4E (0.58) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL1502457 | 0.75 | CYP3A4 (0.58) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL10355251 | 0.75 | CYP3A4 (0.58) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL1501875 | 0.74 | KDM4E (0.56) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| Hydrochloric Acid SCHEMBL10355418 | 0.74 | KDM4E (0.56) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL7445162 | 0.72 | MAPT (0.55) | KDM4ECYP3A4MAPTIDO1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4632930-A | Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-30 | — | — | US | disclosed |