Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18731724 | 0.88 | MAPT (0.40) | MEN1KMT2AMCL1MAPTGAA | |
| SCHEMBL18786340 | 0.83 | GAA (0.39) | MEN1KMT2AMCL1MAPTGAA | |
| SCHEMBL18731829 | 0.82 | GAA (0.41) | MEN1KMT2AMCL1MAPTGAA | |
| SCHEMBL18787216 | 0.81 | TAAR1 (0.38) | MEN1KMT2AMCL1MAPTGAA | |
| SCHEMBL17725990 | 0.79 | KDM4E (0.33) | MEN1KMT2AMAPTGAAMAOA | |
| SCHEMBL18819355 | 0.77 | KDM4E (0.31) | LMNAKDM4EALDH1A1 | |
| SCHEMBL20733760 | 0.77 | ALDH1A1 (0.37) | MEN1KMT2AMAPTGAAKDM1A | |
| SCHEMBL18544801 | 0.75 | — | — | |
| SCHEMBL17073344 | 0.75 | GAA (0.32) | MEN1KMT2AMCL1MAPTGAA | |
| SCHEMBL18731711 | 0.74 | CYP1A2 (0.38) | MEN1KMT2AMAPTGAASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017061810-A1 | DOUBLE SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | 주식회사 엘지화학 | 2017-04-13 | — | — | WO | disclosed |