Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19479667 | 1.00 | MGAM (0.34) | MGAMCYP3A4CYP2C9CYP2C19USP2 | |
| SCHEMBL23315818 | 0.85 | — | — | |
| SCHEMBL19604939 | 0.85 | — | — | |
| SCHEMBL20019513 | 0.84 | CYP2D6 (0.36) | CYP3A4USP2 | |
| SCHEMBL16129441 | 0.83 | — | — | |
| SCHEMBL20096515 | 0.83 | — | — | |
| SCHEMBL19383253 | 0.82 | USP2 (0.41) | MGAMUSP2ALDH1A1CNR1CNR2 | |
| SCHEMBL18500790 | 0.82 | USP2 (0.41) | MGAMUSP2ALDH1A1CNR1CNR2 | |
| SCHEMBL16590506 | 0.81 | — | — | |
| SCHEMBL22872158 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170102349-A1 | ELECTROCHEMICAL METHODS AND COMPOUNDS FOR THE DETECTION OF ENZYMES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170102349-A1 | ELECTROCHEMICAL METHODS AND COMPOUNDS FOR THE DETECTION OF ENZYMES | EPX, DNASE1, DERA | MGAM 19/4885CYP3A4 165/4885CYP2C9 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.